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Gerneral Information

Atomic Force Microscopy (AFM) or Scanning Force Microscopy (SFM) is a very high-resolution type of Scanning Probe Microscopy (SPM), with demonstrated resolution on the order of fractions of a nanometer, more than 1000 times better than the optical diffraction limit. The precursor to the AFM, the Scanning Tunneling Microscope (STM), was developed by Gerd Binnig and Heinrich Rohrer in the early 1980s at IBM Research - Zurich, a development that earned them the Nobel Prize for Physics in 1986.

As the name suggests, the heart of an AFM is a probe that is scanned over the sample surface to build up some form of image. The type of image you get depends on the interaction that is measured by the probe. Images can be produced that reflect many different properties of the sample. The sample height information (topography), usually forms one aspect of the image, but images can also be collected that show other properties, including mechanical, electrostatic, optical, or magnetic information about the sample surface.


Different probes and measurement systems are used for some of the different properties that can be measured, but one requirement is that the interaction between the probe and the sample is localised in some way. The measured signal must be dominated by some small region of the sample close to the tip, so that an image of the sample can be formed as the tip is scanned over the surface. This implies that the interaction must have a strong distance dependence, so that only the nearest parts of the sample contribute to the interaction felt by the tip. The range of the interaction will be one factor in the final resolution of the instrument. When the interaction has a very strong distance dependence, such as the electron tunelling current used in STM, the resolution can be good enough to "feel" individual atoms.

Since the measured signal should be dominated by the small region of probe and sample that are closest together, the actual probe does not need to be an isolated point. The probe can be part of some larger structure that is more convenient to mount and scan. The size of the probe can be relatively large, perhaps hundreds of microns or more, but if the interaction has a short enough range then the signal will be dominated by the very tip region of the probe, so that resolutions can still be achieved in the range from atomic distances to microns.

The idea of a probe measuring a local interaction and building up an image is relatively straightforward, but the actual implementation of a system with a resolution in this range is technically challenging. Many factors came together in the development of scanning probe microscopy, including the development of piezoelectric materials that made it possible to reproducibly position and scan components with a sub-nanometre precision.

Here is a market overview of instruments made by specialist manufacturers and companies around the globe.

Application Notes

Piezoresponse Force Microscopy

This application note presents a primer on the direct and reverse piezoelectric effects and their uses, and the instrumentation and applications of piezoresponse force microscopy... read more


Choosing AFM Probes for Biological Applications

The appropriate choice of AFM probe is crucial for optimal results when imaging biological samples. This application note provides an overview of probes available for biological applications... read more


AFM Applications in Polymer

Polymers are the material of choice in many applications. They can be tailored to have unique properties and are often less expensive, more durable, and more sustainable than other materials. Creating and implementing new polymers requires knowledge of how structure, processing, properties, and performance are related... read more


Characterization of Steel by MFM and KPFM

Examination of steel by the non-contact mode AFM techniques Magnetic Force Microscopy (MFM) and Kelvin Probe Force Microscopy (KPFM) also known as Surface Potential Microscopy... read more


Comprehensive Analyses of Graphene

Graphene shows immense promise in many applications: transistors, sensors, and optoelectronics, to name just a few of them. Flexible and adaptive analyzing methods can support the effective investigation of graphene and accelerate the progress in graphene research and product development... read more


Surfactant Micelles in Aqueous Solution: Critical Resolution in AFM

It’s a widely spread idea that performing AFM in liquids is a rather complicated research approach. Actually, many tasks related to the investigation of molecular structures and complexesin a liquid environment... read more 


Manipulation of Gold Nanoparticles in Liquids Using MAC Mode Atomic Force Microscopy

Precise control of the structure of matter at the nanometer scale will have revolutionary implications for science and technology. Nanoelectromechanical systems (NEMS) will be extremely small and fast, and have applications that range from cell repair to ultrastrong materials... read more


AFM in Cosmetics Research and Product Development

Sensory perception of hair is a primary concern among cosmetic manufacturers. The way hair looks and feels to the touch is related to the structure and properties of hair at the nanometer scale. The Atomic Force Microscope (AFM) offers direct, highly localized, tactile interface with the hair’s outer surface in environments to which hair is usually exposed... read more


Investigation of Solar Cells

While traditional tools are helpful to investigate and improve solar cells, AFM/SPM offers metrology, topography & roughness analysis at much higher resolution than with optical techniques... read more


n-Surf                       FlexAFM                                        TrueMap                                  
MountainsMap ImageJ Image SXM
 AtomicJ PUNIAS FemtoScan
 WSxM  SPIP  Gwyddion







AFM Atomic Force Microscope


Automated AFM: Application flexibility combined with high-end resolution performance. Provides the largest suite of AFM techniques.


NanoMagnetics ezAFM

The ezAFM is an all new Atomic Force Microscope which features excellent performance while being remarkably affordable. It’s ideal for student...


WITec alpha300 RA

A unique combination of chemical and nanoscale imaging in one system: The well-established Raman-AFM combination alpha300 RA was the first...


Bruker Inspire

Bruker’s Inspire delivers, for the first time, highest-resolution nanoscale chemical and property mapping combined with radical productivity advances...


AFMWorkshop TT-AFM

This compact, tabletop Atomic Force Microscope has all the important features and benefits expected from a light lever AFM. The TT-AFM includes...


ATC FemtoScan

FemtoScan - the first Internet-driven microscope. It is operated via Internet using unique software FemtoScan Online. While single user controls the...


Oxford Instruments Asylum MFP-3D Infinity

The FP-3D Infinity is the latest, most advanced AFM in the MFP-3D family. It combines the renowned versatility of its predecessor with new higher...


Park XE-Bio

Single Live Cell Imaging and Scanning Ion Conductance Microscopy: Park XE-Bio is a powerful 3-in-1 bio-research tool that uniquely combines Scanning...


Nanosurf LensAFM

AFM for optical microscopes and 3D profilometers. Mountable on virtually any optical microscope or 3D optical profilometer Equipped with a quality...


NT-MDT Titanium

Revolution Cartridge: The new Revolution Cartridge with multi-probe technology for automated replacement of cantilevers makes a breakthrough in AFM...


JPK NanoWizard 3 NanoScience AFM

AFM for applications in materials and polymer science reaching from single molecule experiments and electrochemistry to organic electronics.


DME Compact Granite with DS95 SPM

The DME compact granite stage provides the possibility of investigating nearly all samples by SPM. From a splitter of a coated wafer to a whole...


Nanonics Academia

The Academia is an affordable AFM system with all the functionality of a research AFM microscope which can function effectively for teaching...


Bruker Dimension Edge PSS

The system incorporates Bruker's proprietary AutoMET control & analysis software, which has been designed specifically to meet the needs of patterned...


Park NX20

More powerful failure analysis solutions: Park NX20 is equipped with unique features that make it easier to uncover the reasons behind device failure...


nanopacific Bio AFM

Nano Pacific now offers a high-precision atomic force microscope to meet the needs of biologists, pathologists and medical scientists. Highly...


Keysight 5600 LS

New 300mm x 300mm and multi-sample 2-inch-wafer stages expand application versatility Largest fully addressable and programmable stage on market...



Automated AFM: Intended for wide application automated monoblock AFM/STM measurement system with a built-in video microscope


Nanosurf NanoFlex Bio

Versatile research AFM for life science. True flexibility with a variety of exchangeable cantilever holders Flat and linear scanning thanks to the...


WITec alpha300 A

Nanoscale Surface Characterization: The WITec Atomic Force Microscope alpha300 A is a reliable, high-quality nano-imaging system integrated with a...


Bruker Dimension FastScan Bio

The Dimension FastScan Bio AFM breaks longstanding barriers to provide routine high-resolution research of biological dynamics, with temporal...


Anfatec Level AFM

AFM-Head including a Top View USB-Camera and Sample Illumination. Our Level AFM offers a wide Spectrum of Measurement Methods: High Resolution...


Nanonics Multiview 2000

The MultiView 2000 series is an advanced single probe scanning probe microscope enabling a variety of modes of AFM/SPM/NSOM imaging. Nanonics has...


Oxford Instruments Asylum Cypher ES Environmental AFM

Oxford introduces the Cypher ES, wich adds full environmental control to the Cypher platform - the highest resolution fast scanning AFM.


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